I’ve done it twice so far (main server and a Raspberry Pi). Although I recall I had some package breakage with the main server (some changes in Podman that did not go well with the migration to pasta, the new rootless network stack), the process was mostly pain free and I could fix things remotely with SSH.

The CUPS server should just work out of the box (not including printer setup) for Windows and Android as well. If the server you use is based on a recent-ish version from OpenPrinting (as it was on Debian 12, so about three years old), it should also work out of the box for iOS.